Introduction	1
The Beginnings	5
Project Goals and Approaches	21
Was the Colony-Stimulating Factor Likely to be a Regulator?	27
The Purification of CSF from Human Urine	33
The Dubious Joys of Bioassays	47
The Discovery and Purification of GM-CSF	59
The Discovery and Purification of G-CSF	71
The Discovery and Purification of Multi-CSF (IL-3)	83
The End of the Beginning: An Appraisal of Progress So Far	93
The Cloning of the CSF Genes	107
The Recombinant CSFs In Vitro and at Last In Vivo	123
The Clinical Use of the CSFs	139
The Cloning and Characterization of Receptors for the CSFs and Other Regulators	153
The Role of the CSFs in Myeloid Leukemia	167
In Vivo Manipulation of CSF Genes	187
The Bottom Lines	197
Appendix	203
Suggested Further Readings	209
Index	211

Copyright ©2007 AlphaMed Press. All Rights Reserved.